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Have you or a loved one been diagnosed with Mesothelioma or Lung Cancer from asbestos?  You are not alone.  We want to help you and your family.  Asbestos Trust Fund money may be available to you, and you don't have to go to court.  This money can be used for medical bills and treatment, and provide future financial security for your loved ones.  Please call us today to get the facts.  Toll Free 1-866-777-2557 or fill out our online contact form and a Vermont Mesothelioma Lawyer will contact you within 24 hours to answer any questions you might have.  This is a free consultation, and there are no legal fees or costs to you unless you receive money.  Operators are standing by.  Call now.  Mesothelioma Lawyers Vermont






































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Genetic Research
There is research being conducted quite frequently to determine the relationship between genetics and mesothelioma development.  It is known that mesothelioma is a malignancy that develops as a result of asbestos exposure.  There are some other factors that may actually increase the chances of an individual being diagnosed with mesothelioma.
Some researchers are actually claiming that certain viruses and gene expressions may contribute to why individuals with the same asbestos exposure have different medical outcomes.  The researchers are trying to determine the reason that some individuals develop mesothelioma while some individuals do not develop mesothelioma when the asbestos exposure was the same.  The research is actually pointing towards gene expression as one of the possible factors behind this phenomena. 


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BAP1 Gene
One of the genes being evaluated is the BAP1 gene.  The BAP1 gene functions as a tumor suppressor.  A tumor suppressor gene functions exactly as it sounds:  it works to suppress the formation of tumors.  It has been noted that in individuals who are diagnosed with mesothelioma have a mutation in this particular gene.  The mutation in the gene is thought to interfere with normal functioning.  Interference with normal functioning, creates an environment in which tumor suppression is not occurring.  When this gene is not suppressing tumor formation, this allows for tumors to form.  Mesothelioma has the potential to then develop if the appropriate conditions are met.  Asbestos exposure and subsequent inhalation of the asbestos fibers can result in mesothelioma.  Diminished tumor suppression capability and increased asbestos exposure can result in the perfect storm that results in the deadly disease known as mesothelioma.  The information provided is still undergoing research.  There has not been a formal direct link between mutated BAP1 gene and development of mesothelioma.  However, the researchers believe that this link will be made in the future.


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SV40 Virus
Another contributing factor that may result in increased risk of mesothelioma development is the SV40 virus.  The SV40 virus is a virus that is native to the Simian species.  The Polio vaccine was developed in the simian species, and in some instances the SV40 virus was transmitted into the vaccine.  The vaccine was contaminated and then given to many individuals seeking protection from the debilitating disease known as Polio.  The SV40 virus is thought to result in mutations in the tumor suppressor genes.  As discussed above, with mutations that inactivate these tumor suppressor genes the perfect environment for tumor development occurs.  With asbestos exposure, the individual has an increased chance of developing mesothelioma.  The relationship between the SV40 virus an mesothelioma is a very far stretch.  It has been a topic of controversy in the medical field, and pretty much disproven.  There is still research being conducted to determine if there is any validity to this claim.


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Conclusion
The important message to take from this article, is that there may be a genetic component to mesothelioma.  Mesothelioma is a deadly disease.  If there is a genetic component that can help predict who is at the highest risk of developing this disease it will allow for early detection.  Early detection means better treatment outcomes for those with this disease.  Research is the future of medicine.


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